Chronic oxidative stress is linked to a wide range of diseases, including: Cardiovascular disease : ROS damage endothelial cells lining blood vessels, promoting atherosclerosis and hypertension.[9] Neurodegenerative disorders : Oxidative damage to neurons is a key driver in conditions like Alzheimers, Parkinsons and ALS.[10] Diabetes and insulin resistance : Oxidative stress impairs insulin signaling and worsens glycemic control.[10] Cancer : DNA mutations caused by free radical damage may initiate or accelerate tumor development.[11] Autoimmune conditions : Oxidative stress can trigger inflammatory pathways, contributing to immune dysregulation.[9] Even outside of these conditions, oxidative stress contributes to fatigue, slower recovery, immune suppression and premature aging at the cellular level
After removing the duplicates, 255 potential targets of HT were obtained, and these 255 targets were entered into the UniProt database to be converted into gene symbols
Kresch E, Efimenko I, Gonzalez D, Rizk PJ, Ramasamy R
Development of a temporary threshold shift model of chronic noise-induced tinnitus with evidence of altered auditory signaling pathway inhibition
